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Fig. 3 | Genome Biology

Fig. 3

From: txci-ATAC-seq: a massive-scale single-cell technique to profile chromatin accessibility

Fig. 3

Cell type identification and marker assessment in mouse whole brain sample. a UMAP projection of mouse brain nuclei (n = 49,765). Nuclei are colored by their predicted cell type. b Z-scored average gene activity score per cluster plotted as a heatmap. Clusters are arranged by hierarchical clustering. Marker sets are from Brain Map marker genes. c Boxplots of FRiP per technology using a unified peak set. Numbers over the boxplot reflect the fold-change of medians in comparison to txci-ATAC-seq. Stippled line is the median value for txci-ATAC. d Boxplots of transcription start site (TSS) enrichment across technologies. Numbers over the boxplot reflect the fold-change of medians in comparison to txci-ATAC-seq. Stippled line is the median value for txci-ATAC. e LIGER integrated UMAP projection of technologies (n = 75,845 cells) colored by technology (left) and cell type (right)

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