Fig. 2From: CancerLocator: non-invasive cancer diagnosis and tissue-of-origin prediction using methylation profiles of cell-free DNAThe mixture model of methylation level (x) in a patient’s plasma cfDNA for different burdens of ctDNAs from the tumor type t. Note that x, u, and v are the methylation levels of a single CpG cluster k in cfDNA, solid tumor, and normal plasma, respectivelyBack to article page